Rotational Wavelet Filters for Analysis of Brain MRI in Detection of Alzheimer’s Disease

Abstract

In this paper, a method is suggested for multi directional analysis of Magnetic Resonance Image (MRI) scans for detection of Alzheimer’s disease (AD). This is a novel technique which utilizes, two-dimensional (2-D) rotated complex wavelet filters (RCWF) for feature identification. DTCWT identifies the features in 6 directions (±15⁰±45⁰, ±75⁰) while RCWT identifies the features in different 6 directions (-30⁰,0, +30⁰, +60⁰, +90⁰, +120⁰), which enhances the directional selectivity of the transform coefficients and results in well description of corresponding textures. Dual-tree rotated complex wavelet transform (DT- RCWF) and dual-tree complex wavelet transform (DT- CWT) are applied to the sample images at a time thus the transform coefficients in twelve different directions is obtained simultaneously. The obtained transform coefficients are used for calculation of various texture features such as energy, entropy and standard deviation. The obtained parameters form the feature vectors which are given as input to the classifiers to get the input classified as Normal control or AD sufferer. This proposed algorithm produces results which are superior in terms of accuracy, feature extraction rate, sensitivity, specificity, precision and recall necessary to realize the efficiency of diagnosis of Alzheimer’s Disease as compared to other existing methods.